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              長期缺覺為什么會反應遲鈍?可能和這一腦區神
                你是不是有這樣的經歷,持續無法入睡之后,會變得反應遲鈍?
               
                當地時間11月6日,一篇發表于《自然-醫學》期刊的研究論文表明,睡眠剝奪之后出現的認知退步可能和人腦內側顳葉內神經活動的減弱有關。
               
                睡眠剝奪曾經是一種殘酷的刑罰。隨著人類對自身的日益了解,睡眠剝奪被認定和健康緊密相關。長期慢性睡眠剝奪會增加各種疾病的患病風險,比如高血壓、糖尿病、抑郁癥等。更令人擔憂的是,睡眠不足引起的認知退步會導致行為障礙,從而引發意外事故,導致死亡。
               
                之前,科學家認為,睡眠剝奪引起的認知后退和丘腦、額頂部環路有關,但內在機制一直不明。
               
                此次,來自以色列特拉維夫大學和美國威斯康星大學麥迪遜分校、加州大學洛杉磯分校的研究人員以神經外科病人為測試對象,讓他們在被剝奪睡眠前后,分別完成精神運動警覺性任務,并用顱內電極記錄單個神經元的活動和局部場電位。精神運動警覺性任務(PVT)是常用的警覺性評價方法,主要檢測被試者對視標刺激的持續注意力和反應時間。
               
                他們發現,就在被試者出現認知失誤、反應變慢之前,內側顳葉內的神經活動往往出現減弱、延遲的現象。研究人員認為,這表明該區域神經活動的減弱和睡眠剝奪引起的認知后退有關。
               
                接下來,研究人員將繼續探究這些減弱的神經活動模式在其他腦區是否也存在。在解答睡眠剝奪到底是如何影響神經活動的問題之前,研究人員還有諸多工作需完成。
               
                
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